Overall objectives:

1 - OBJECTIVES:
1.1 - To acquire basic theoretical knowledge of Organic Chemistry to structural level, mastering the rules of nomenclature and recognizing the characteristics of functional groups and the various types of isomerism.
1.2 - To recognize the structural aspects of the various types of biomolecules: lipids, carbohydrates, proteins and nucleic acids.
1.3 - To relate the polarity and shape of molecules with their physical, chemical and physiological properties
1.4 - To relate the functionality of small and relatively simple molecules with that of complex molecules that are involved in the biochemical processes.
2 - SKILLS TO BE ACQUIRED BY THE STUDENT:
2.1 - Development of visualization and spatial reasoning
2.2 - Development of concentration capacity, critical spirit and autonomous study
2.3 - Working as a team outside the usual social group, developing leadership and negotiation skills
2.4 - Ability to relate the knowledge acquired with the phenomena observed in everyday life

Syllabus:

1 - Carbon compounds. Intermolecular forces. Dipolar moment. Shape and polarity of molecules;
2 - Hybridization and geometry of hybrid orbitals. Resonance;
3 - Nomenclature of functional groups;
4 - Types of isomerism. Isomer stability;
5 - Alkanes and Cycloalkanes. Physical and physiological properties. Conformational analysis. Types of projection, threedimensional interpretation;
6 - Stereochemistry. Chirality. Fischer projections. Optical activity. Meso compounds;
7 - Arenes and Aromaticity;
8 - Biomolecules;
9 - Simple and complex lipids. Relationship of structural elements and geometry with physiological properties;
10 - Amino acids, peptides and proteins. Stereochemistry and acid-based behavior. Peptide binding. Primary, secondary and tertiary structure. Quaternary structure of proteins;
11 - Carbohydrates. Aldoses and ketoses. Ketals and hemiketals, Reducing sugars. Chain extension. Glycosidic;
12 - Nucleosides, Nucleotides and Nucleic Acids.

Literature/Sources:

N/A , Solomons Organic Chemistry + Study guide , Publisher Wiley
Morrison & Boyd , Química Orgânica , Fundação Calouste Gulbenkian,
Carey , Organic Chemistry , accessible online
Morais & Silva , 2004 , Estereoquímica em Química Orgânica , Ed Silabo

Assesssment methods and criteria:

Classification Type: Quantitativa (0-20)

Evaluation Methodology:
This UC comprises 32 hours of theoretical classes and 32 hours of theoretical-practical classes divided for 16 weeks. In the theoretical, teacher teaching is accompanied by multimedia projection, painting use and manipulation of molecular models; The practical theoretical classes are held in the room, involving weekly series of exercises, the use of molecular models and programs that allow 3D visualization, determination of intra- and intermolecular binding energies (ChemDraw, HyperChem). The evaluation of this UC consists of: a) 2 written tests (weight of 70%); The minimum score in each test is 8 values. b) 1 monograph (individual or in group) on a molecule of choice and its presentation before the whole class, using the format that the group finds most appropriate (weight of 30%).