Overall objectives:

1 - i) acquisition of solid knowledge in the disciplines of physical anthropology and Human Ecology as well as Human Genetics and Immunology
2 - ii) Domain of the principles, concepts and tools of each of the areas addressed and its application to practical and theoretical problems
3 - iii) Development of a critical thinking and scientific curiosity, encouraging the use of autonomous literature in specialized journals
4 - iv) consolidation and integration of knowledge acquired previously in related disciplines such as Genetics, Cell Biology and Biotechnology
5 - v) Development of skills for research, recognizing its importance in the increase of knowledge as well as professional development
6 - vi) Development of skills related to oral and written communication, with the concepts and terminology appropriate to the subject areas, and synthesis capacity.

Syllabus:

1 - Part 1. Physical anthropology and human ecology. Hominid evolution. Anthropometry: morphological variation, differences between sexes and races, age determination. Biotic and abiotic factors in human populations.
2 - Part 2 Human Genetics (genome organization, genetic variability, evolution of chromosomes X and Y. Forensic Genetic polymorphisms of DNA, non-­human DNA, analysis of biological samples, genetic identification, clinical genetics databases, studies and methodology in familiar genetics. Screening for gene mutations in patients. Epigenetics. Identification of genes in Mendelian disorders
3 - Part 3 The immune system, lymphocytary diversity, response immune innate, HLA: structure and polymorphisms, activation of immune response. Common genetic disorders of the immune system. Molecular mimicry and autoimmunity, transplant rejection, HLA typing and distribution, association with pathologies.

Literature/Sources:

Arosa F, Cardoso E, Pacheco F. , 2012 , Fundamentos de Imunologia, 2nd Ed , Lidel
Ferembach D Susanne C, Chamla M. , 1986 , Manuel d?anthropologie physique , Editions du CNRS
Harrison G, Tanner J, Pilbeam D, Baker P , 1988 , Human Biology. An introduction to human evolution, variation, growth, and adaptability. , Oxford University Press
Hiernaux J. , 1988. , Diversidade Biológica Humana. , Calouste de Gulbenkian
Muehlenbein M. , 2010. , Human Evolutionary Biology. , Cambridge University Press
Ulijaszek S, Strickland S , 1993 , Seasonality and Human Ecology , Cambridge University Press
Weiner J, Lourie J , 1981 , Practical Human Biology , Academic Press
Korf B, Irons M. , 2013 , Human Genetics and Genomics, 4th Ed , Wiley­Blackwell Pub
Lewis R. , 2011 , Human Genetics, 11th Ed , McGraw­Hill Science
Jobling M et al , 2013 , Human Evolutionary genetics, 2nd Ed , Garland Science
Sompayrac L. , 2012 , How the Immune System works, 4th Ed , Wiley­Blackwell Pub
Parham P. , 2009 , he Immune Systems, 4th Ed , Garland Science

Assesssment methods and criteria:

Classification Type: Quantitativa (0-20)

Evaluation Methodology:
Lectures: 60 minutes, 2 times a week. Semi­expository lessons, based on powerpoint and other educational tools available, but in which we encourages the active participation of students. Presentations are prepared based on updated textbooks and publications in journals of science. Theoretical­practical: 120 minutes, 1 time per week divided by half. Scripts to support theoretical foundations about each theme, as well as supporting bibliography of recommended search tools and exercises will be available. The class begins with the framework of a case­study, followed by analysis and discussion and problem solving.